Pemetrexed EP Impurity B Tetrasodium salt CAS 1802552-04-0 (free base)
| CAS No. | 1802552-04-0 (free base) |
| Molecular Formula | C40H36N10O13 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Pemetrexed EP Impurity B Tetrasodium salt (CAS 1802552-04-0 (free base), C40H36N10O13Na) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Pemetrexed EP Impurity B Tetrasodium salt (C40H36N10O13Na) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 28.0, corresponding to approximately 28 ring(s) or double-bond equivalent(s). With a molecular weight of 887.77 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pemetrexed EP Impurity B Tetrasodium salt under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C40H36N10O13 4*Na |
| Molecular Weight | 887.77 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 28.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 10 |
Related Pemetrexed Standards
- Pemetrexed Impurity 21 (CAS 1001-19-0)
- Pemetrexed Impurity 11 (CAS 100643-27-4)
- Pemetrexed Impurity 22 (CAS 1075-59-8)
- Pemetrexed Impurity 54 (CAS 1265908-58-4)
- Pemetrexed EP Impurity D Trisodium salt (CAS 1265908-59-5)
- Pemetrexed Impurity (CAS 1265908-60-8)
- Pemetrexed Impurity (CAS 1265908-61-9)
- Pemetrexed Impurity 53 (CAS 1320346-37-9)
Recommended Standards
- Avanafil Impurity 88 (CAS 2250243-52-6)
- Elagolix lmpurity 61 (CAS 2486454-65-1)
- Cefdinir Impurity 29 (CAS CATO-C4X-121029)
- NO-Feng-PDiPPRa (CAS 1005495-74-8)
- 3-(3-Aminopropyl)-5,5-dimethylimidazolidine-2,4-dione (CAS 66387-39-1)
- 2-(4-Bromophenoxy)tetrahydropyran (CAS 36603-49-3)
- 3-(4-Nitrophenyl)propan-1-amine hydrochloride (CAS 56946-60-2)
- 3-Hydroxy-6-methyl-3-(trifluoromethyl)indolin-2-one (CAS 128350-88-9)
- 2-(Tetrahydropyran-2-yloxy)phenol (CAS 21645-25-0)
- Casein Kinase II Receptor Peptide (CAS 198481-81-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com